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PROFYLE: Important Information for Patients and Families

PROFYLE (PRecision Oncology For Young peopLE) is a pan-Canadian research project for children and young adults ages 29 and under who have been told they are out of treatment options, giving them another chance.

Only oncologists can enroll patients in PROFYLE -- please check with your doctor for more information. Your oncologist can work with the site leads listed below to determine if your child meets the project's eligibility criteria. 


British Columbia Children's Hospital

Vancouver, British Columbia

Drs. Rod Rassekh and Rebecca Deyell

BC Cancer

Vancouver, British Columbia

Drs. Alannah Smrke and Janessa Laskin

Alberta Children's Hospital

Calgary, Alberta

Drs. Victor Lewis and Geoff Cuvelier

Tom Baker Cancer Centre

Calgary, Alberta

Dr. Jan-Willem Henning

Stollery Children's Hospital

Edmonton, Alberta

Dr. Lucie Pecheux

Saskatoon Cancer Centre / Jim Pattison Children's Hospital

Saskatoon, Saskatchewan

Dr. Saima Alvi

CancerCare Manitoba

Winnipeg, Manitoba

Drs. Issai Vanan, Stephanie Villeneuve and Sapna Oberoi

Children’s Hospital London Health Sciences Centre

London, Ontario

Dr. Alexandra Zorzi

McMaster Children's Hospital

Hamilton, Ontario

Dr. Carol Portwine

The Hospital for Sick Children

Toronto, Ontario

Drs. Anita Villani and David Malkin

University Health Network (Princess Margaret Cancer Centre)

Toronto, Ontario

Drs. Mark Minden, Philippe Bedard, Warren Mason and Christine Elser

Sinai Health (Mount Sinai Hospital)

Toronto, Ontario

Dr. Rebecca Gladdy

Kingston General Hospital

Kingston, Ontario

Dr. Laura Wheaton

Children's Hospital of Eastern Ontario

Ottawa, Ontario

Drs. Donna Johnston, Lesleigh Abbott, Sarah Sawyer and Raveena Ramphal

CHU de Québec (Laval University)

Québec, Québec

Drs. Lamia Naccache and Raoul Santiago

Montreal Children’s Hospital (McGill University)

Montreal, Québec

Drs. Nada Jabado and Catherine Goudie

CHU Sainte-Justine (University of Montreal)

Montreal, Québec

Drs. Thai Hoa Tran and Nicolas Prud-homme

CHU de Sherbrooke (Sherbrooke University)

Sherbrooke, Québec

Dr. Josée Brossard

IWK Health Centre

Halifax, Nova Scotia

Dr. Meghan Pike

Janeway Children's Health and Rehabilitation Centre and Dr. H. Bliss Murphy Cancer Centre

St. John's, Newfoundland

Drs. Paul Moorehead, Erin Powell and Jacqueline Costello

PROFYLE Consortium Sites


For more information about clinical trials, please see the U-Link Canada website.

For more information about financial support for families who have to travel to access an early phase clinical trial, please see the U-Link Patient and Family Fund.

For more information about financial support programs for families, please see the resources listed on the U-Link Canada website.

For more information, you can also read: